COPOLYMERS OF 2-METHYL-5-VINYL-PYRIDINE AND N-VINYLPYRROLIDONE, ACTIVATING PRODUCTION OF INTERLEUKIN-1, AND USE THEREOF AS ANTI-CANCER AGENTS Russian patent published in 2011 - IPC C08F226/10 A61K31/79 

Abstract RU 2430932 C1

FIELD: chemistry.

SUBSTANCE: disclosed is use of copolymers of N-vinyl pyrrolidone of general formula (I), where the monomer link M is a fragment of 2-methyl-5-vinyl tetrazole (MVT) or 2-methyl-5-vinyl pyridine (MVP) and content of the monomer links n is equal to 25-50 mol %, and viscosity-average molecular weight Mµ of the copolymer depends on the nature of M: if M is MVT, Mµ=30-50 kDa; if M is MVP, Mµ=15-28 kDa, as activators of production of interleukin-1-alpha and interleukin-1-beta and anticancer agents. .

EFFECT: wider range of biologically active compounds suitable for use as activators of production of interleukin-1 and anti-cancer agents.

3 cl, 4 tbl, 5 ex

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RU 2 430 932 C1

Authors

Kedik Stanislav Anatol'Evich

Panov Aleksej Valer'Evich

Zajtsev Maksim Andreevich

Cherta Julija Vjacheslavovna

Dates

2011-10-10Published

2010-10-29Filed