THERAPEUTIC COMBINATION CONTAINING LUNG SURFACTANT AND STEROID Russian patent published in 2014 - IPC A61K35/12 A61K31/66 A61K38/02 A61K31/573 A61P11/00 

Abstract RU 2533450 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: what is presented is a group of inventions involving: using poractant alfa in a dose of 100 to 200 mg/kg in a combination with beclomethasone dipropionate in a dose of 0.6 to 0.8 mg/kg for preventing bronchopulmonary dysplasia (BPD) (versions) for producing a therapeutic agent for preventing BPD, a respective pharmaceutical composition and a kit for the same application.

EFFECT: reducing the levels of pulmonary oxidative stress markers, but is also combined with improving the external pulmonary mechanics: a synergetic reduction of MAP (mean airway pressure) has been shown.

14 cl, 3 tbl

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RU 2 533 450 C2

Authors

Giossi Massimo

Razzetti Roberta

Chiesi Paolo

Dates

2014-11-20Published

2010-05-21Filed