SYSTEM FOR INTRAVENOUS INJECTION OF RUBIDIUM CHLORIDE 82RB FROM GENERATOR Russian patent published in 2014 - IPC A61M5/145 A61M36/06 

FIELD: instrument making.

SUBSTANCE: invention relates to systems for intravenous injection of radiopharmaceuticals (RP) from a generator and can be used in diagnostics of myocardial perfusion and cancer diseases by means of a positron emission tomography method. The system includes a generator with input and output fittings, a control unit, and an injection pump, an eluent tank, four three-way valves, pipelines, pressure and radioactivity sensors, sterilising filters, a unidirectional valve, a syringe and a catheter for intravenous infusion. The generator has input and output holes, the first of the three-way valves is connected to the eluent tank and to an elution pump, the second one is fixed on the output fitting of the generator, connected to an eluate conveying pipeline, and its end is provided with the second sterilising filter and the third three-way valve connected to the unidirectional valve, to the catheter for intravenous infusion and the syringe. The sterilising filters are equipped with built-in air valves, the pressure sensor is installed between the first three-way valve and the first sterilising filter, the radioactivity filter is installed before the second sterilising filter, the fourth three-way valve is located on the input fitting of the generator, and the unidirectional valve is located between the second sterilising filter and the third three-way valve. The control unit can control the elution pump, 1, 2 and 4 three-way valves and monitor the pressure and radioactivity sensors. The system allows measuring an activity of a preparation immediately at its injection to a patient, provides the injection of the required preparation dose in an automatic mode, ensures the assessment of the state of a sorbent of the generator column by means of the pressure sensor, differs by a simple design and is intended for assembly directly at PET centres.

EFFECT: software allows avoiding the need for manual calculations of radioactivity at calibration of the instrument.