METHOD OF OBTAINING N-ACYLBIPHENYLALANINE Russian patent published in 2014 - IPC C07C231/12 C07C231/10 C07C233/47 C07C233/51 C07C233/87 

FIELD: chemistry.

SUBSTANCE: claimed invention relates to a method of obtaining a compound of formula (2-a), where the compound of formula (2-a) preferably corresponds to formula (2), and where R1 represents (C₁-C₇)alkyl, preferably, methyl, or (C₆-C₁₀)aryl, preferably, phenyl, including the interaction of a compound of formula (1-a), where the compound of formula (1-a) preferably corresponds to formula (1), and where R1 corresponds to the definition for the compound of formula (2-a), with water in order to obtain the compound of formula (2-a). The interaction is realised at a temperature from room temperature to reflux boiling temperature. The invention also relates to a method of obtaining a compound of formula (3) or its salt, where the compound of formula (3) preferably corresponds to formula (3-a), and where R1 represents (C₁-C₇)alkyl, preferably, methyl, or (C₆-C₁₀)aryl, preferably, phenyl, including processing the compound of formula (2-a) or its salt, where the compound of formula (2-a) preferably is the compound of formula (2), where R1 represents (C₁-C₇)alkyl, preferably, methyl, or (C₆-C₁₀)aryl, preferably, phenyl, under conditions of hydration in order to obtain the compound of formula (3). The hydration conditions include the application of hydrogen and palladium, preferably, palladium on activated coal. The invention also relates to the compound of formula (2-a) or its salt, where the compound of formula (2-a) preferably corresponds to formula (2), where R1 represents (C₁-C₇)alkyl, preferably, methyl.

EFFECT: method of obtaining biphenylalanine derivatives, providing advantages in the industrial respect.

14 cl, 9 ex