FIELD: medicine.
SUBSTANCE: invention refers to biotechnology. There are described a pair of primers and real-time PCR probes designed for diagnosing Avellino corneal dystrophy. Using the pair of primers and the probe according to the present invention can provide diagnosing the Avellino corneal dystrophy by performing the more rapid and accurate technique as compared to those implying a DNA chip or PCR.
EFFECT: invention enables the accurate diagnosis of the absence or presence of BIGH3 gene mutation responsible for the Avellino corneal dystrophy, in exon 4.
4 cl, 2 dwg, 2 ex
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