METHOD OF DIAGNOSING OXIDATIVE STRESS BY MEASURING EXPRESSION OF OXYGEN-SENSITIVE GENES (VERSIONS) Russian patent published in 2014 - IPC C12Q1/68 

Abstract RU 2534821 C2

FIELD: medicine.

SUBSTANCE: group of inventions relates to the field of medicine and molecular biology. The method includes measuring the expression of the following oxygen-sensitive genes: Pdk4, Nid2, Golph2, Actr1a, Api5, Mrp13, Scn7a, Acox3, Lamr1, Sv2b, Stmn2, Trpc3, Crebzf, Herc1, Ssc1, Snrpb, Zfhx1b, sc125b, Rn. 48050, Rn. 42485, MPP3, AI 101224, Abca1, Appbp1, Rn. 96234, Nptxr, Rn. 16755, Vamp2, Ghr, Calm1, Cyp51, and ID1, and by the determined difference in the level of expression of the said genes in animals which were subjected and which were not subjected to an influence of oxidative stress, a conclusion about the presence of oxidative stress in a mammal is made.

EFFECT: method makes it possible to diagnose the state of oxidative stress in an organism both in time and after the influence of oxidative stress.

6 cl, 2 dwg, 2 tbl, 2 ex

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Authors

Shkurat Tat'Jana Pavlovna

Gus'Kov Gleb Evgen'Evich

Bibov Mikhail Jur'Evich

Ryzhkov Pavel Aleksandrovich

Dates

2014-12-10Published

2012-05-18Filed