ARTIFICIAL NUCLEIC ACID MOLECULES COMPRISING 5'TOP UTR Russian patent published in 2018 - IPC C12N15/67 C12N15/85 A61K39/00 A61K48/00 A61K38/00

Abstract RU 2660565 C2

FIELD: biotechnology.

SUBSTANCE: invention relates to biotechnology, specifically to an artificial nucleic acid molecule. Invention further relates to the use of such an artificial nucleic acid molecule encoding therapeutic peptides or proteins in medicine for gene therapy and / or genetic vaccination.

EFFECT: synergistic effect due to the presence of 3'UTR albumin gene and 5'UTR element, which is derived from the TOP gene, increases the stability and prolongs the expression of the encoded protein.

83 cl, 30 dwg, 5 tbl, 5 ex

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RU 2 660 565 C2

Authors

Tess Andreas

Dates

2018-07-06—Published

2013-03-27—Filed