FIELD: medicine.
SUBSTANCE: invention relates to medicine and represents a method of treating hematologic malignant diseases, which includes the introduction to a subject of a therapeutically effective quantity of an Aurora kinase inhibitor simultaneously or successively with an anti-CD20 antibody, where the Aurora kinase inhibitor represents 4-{[9-chloro-7-(2-fluoro-6-methoxyphenyl)-5H-pyrimido [5,4-d][2]benzazepin-2-yl]amino}-2-methoxybenzoic acid or its pharmaceutically acceptable salt and where the anti-CD20 antibody represents rituximab.
EFFECT: invention provides more efficient treatment in comparison with monotherapy.
8 cl, 4 ex, 27 tbl
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Authors
Dates
2014-12-10—Published
2009-12-15—Filed