FIELD: chemistry.
SUBSTANCE: invention relates to compounds selected from the following compounds 73 and 75, and their pharmaceutically acceptable salts, which can find application in the treatment of cancer or leukemia. The invention also relates to pharmaceutical compositions comprising said compounds, use of said compounds for the manufacture of a medicament for the treatment of cancer or leukemia, and a method of treatment of these diseases. Compound 73, structure
2-(2.2-dioxo-2.3-dihydro-1H-2lyamda*6*-benzo[c]thiophen-5-ylamino)-9-(2-ftorfinil)-5metil-5,7,8,9-tetragidropiramido[4.5-b][1.4]diazepin-6-one; Compound 75, structure
2-(2.2-dioxo-2.3-dihydro-1H-2lyamda*6*-benzo[c]thiophen-5-ylamino)-5-methyl-phenyl-5,7,8,9-etrahydropyrimido[4.5-b][1.4]diazepine-6.
EFFECT: high effectiveness of compounds.
7 cl, 3 dwg, tbl 8, 9 ex
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