FIELD: medicine.
SUBSTANCE: papillary dermis of the intact skin is examined to determine the expression level of the following immunohistochemical markers per 1 mcm2: elastin, fibrillin, amyloid P, vitronectin, fibulin-5. If the elastin value is less than 11.0%, the fibrillin value is less than 6.0%, the amyloid P value is less than 0.2%, the vitronectin value is less than 0.1%, and the fibulin-5 value is more than 57.0%, the biological age of the dead body is considered to be 5-10 years. If the elastin value is 43.0-64.0%, the fibrillin value is 23.0-47.0%, the amyloid P value is 3.5-7.8%, the vitronectin value is 4.6-6.8%, and the fibulin-5 value is 0.5-4.7%, the biological age of the dead body is considered to be 35-45 years. If the elastin value is less than 3.0%, the fibrillin value is less than 1.5%, the amyloid P value is more than 27.0%, the vitronectin value is more than 12.0%, and the fibulin-5 value is less than 0.1%, the biological age of the dead body is considered to be 70-85 years.
EFFECT: invention enables determining the individual's biological age and solving the problems taken up with forensic surgeons by the investigating authorities more objectively.
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Authors
Dates
2014-12-10—Published
2013-11-25—Filed