FIELD: medicine, pharmaceutics.
SUBSTANCE: claimed invention relates to novel compounds of formula (I) or their pharmaceutically acceptable salts used for the treatment or prevention of diseases, mediated by vitamin D receptors, as well as to a pharmaceutical composition, containing the said compounds. . In formula (I) a carbon atom, which X is bound to, has an S or R configuration, X represents -CH2OC(O)R2, Y1 and Y2 each represents hydrogen, Y3 and Y4 together form a methylene group, Z1 represents fluorine, a hydroxyl group or hydroxymethyl, Z2 represents fluorine or a hydroxyl group, R2 represents C1-10alkyl, C1-10alkylamino, C1-10alkylcarbonyloxyC1-10alkyl or hydroxyC1-10alkyl.
EFFECT: obtaining pharmaceutically acceptable salts, used for the treatment or prevention of disorders, mediated by the vitamin D receptors.
5 cl, 4 dwg, 6 tbl, 19 ex
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Authors
Dates
2014-12-10—Published
2008-11-20—Filed