METHOD FOR ASSESSING SEVERITY AND POSSIBLE OUTCOME OF RETINOPATHY IN PREMATURE NEWBORN CHILDREN Russian patent published in 2014 - IPC G01N33/48 

FIELD: medicine.

SUBSTANCE: at the first stage of a subtotal vitrectomy, the vitreous body is sampled with its biochemical parameters to be analysed. In an air-free environment, the vitreous body samples are analysed to determine the following values at 37°C by means of an automatic blood gas and acid-base balance analyser: pH, partial carbon dioxide pressure pCO₂, actual bicarbonate ion $$(HC{O}_3^{-})$$ and BE base excess/deficiency. If the ophthalmoscopic examination shows signs of exudative-proliferative reactions in the posterior eye segment, with the vitreous body pH <6.9, the partial carbon dioxide pressure pCO₂<8 mm Hg, actual bicarbonate concentration $$HC{O}_3^{-}<2$$ mmole/l and BE<-25 mmole/l, the course of retinopathy is considered to be aggressive with a low probability of the formation of adequate visual functions in the disease outcome.

EFFECT: method enables assessing the severity and potential outcome of retinopathy in newborn children as shown by analysing the acid-base balance of the vitreous body.

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