DIBENZOFURAN OXIME DERIVANTS WITH ANTICONVULSANT AND NEUROPROTECTIVE ACTIVITY Russian patent published in 2021 - IPC C07D307/91 A61K31/343 A61P25/08 

Abstract RU 2744758 C2

FIELD: chemistry.

SUBSTANCE: invention relates to a group of derivatives of O-oxime 3,4,6,7,8,9-hexahydrodibenzo[b,d]furan-1(2H)-one of a general formula , wherein .

Invention also relates to use of derivatives of O-oxime 3,4,6,7,8,9-hexahydrodibenzo[b,d]furan-1(2H)-one of the abovementioned general formula, wherein

,

and to method of synthesis of such compounds.

EFFECT: synthesis of such compounds that may be used in medicine as anticonvulsant and neuroprotective products and products with combined anticonvulsant and neuroprotective activity for treatment of epilepsy and paroxysmal conditions.

5 cl, 9 tbl, 8 ex

Similar patents RU2744758C2

Title Year Author Number
AMINOALKYL DERIVATIVES OF DIBENZOFURANONE OXIME EXHIBITING ANTICONVULSANT ACTIVITY 2020
  • Voronina Tatyana Aleksandrovna
  • Zhmurenko Lyudmila Aleksandrovna
  • Mokrov Grigorij Vladimirovich
  • Litvinova Svetlana Aleksandrovna
  • Ivashova Dinara Mikhajlovna
  • Gudasheva Tatyana Aleksandrovna
  • Durnev Andrej Dmitrievich
RU2773021C2
CINNAMOYL DERIVATIVES OF DIBENZOFURANONE OXIME WITH ANTICONVULSANT ACTIVITY 2023
  • Seredenin Sergej Borisovich
  • Mokrov Grigorij Vladimirovich
  • Voronina Tatyana Aleksandrovna
  • Litvinova Svetlana Aleksandrovna
  • Zhmurenko Lyudmila Aleksandrovna
  • Biryukova Valentina Evgenevna
  • Shangin Stanislav Vladimirovich
  • Grigorkevich Oksana Sergeevna
  • Gudasheva Tatyana Aleksandrovna
  • Vakhitova Yuliya Venerovna
RU2810250C1
4-BENZOYLPYRIDINE OXIME DERIVATIVES HAVING ANTICONVULSANT ACTIVITY AS AGENTS FOR TREATMENT OF EPILEPSY AND PAROXYSMAL STATES 2016
  • Durnev Andrej Dmitrievich
  • Voronina Tatyana Aleksandrovna
  • Litvinova Svetlana Aleksandrovna
  • Nerobkova Lyubov Nikolaevna
  • Gajdukov Igor Olegovich
  • Gudasheva Tatyana Aleksandrovna
  • Zhmurenko Lyudmila Aleksandrovna
  • Mokrov Grigorij Vladimirovich
RU2643091C2
DERIVATIVES OF 4-PHENYLPYRROLIDONE WITH ANTICONVULSANT AND NOOTROPIC ACTIVITY AS MEANS OF TREATING EPILEPSY AND PAROXYSMAL CONDITIONS 2017
  • Voronina Tatyana Aleksandrovna
  • Kovalev Ivan Georgievich
  • Litvinova Svetlana Aleksandrovna
  • Nerobkova Lyubov Nikolaevna
  • Zhmurenko Lyudmila Aleksandrovna
  • Mokrov Grigorij Vladimirovich
  • Gudasheva Tatyana Aleksandrovna
  • Durnev Andrej Dmitrievich
RU2748419C2
DRUG FOR IMPROVING BLOOD SUPPLY OF ISCHEMIZED BRAIN 2019
  • Mirzoyan Ruben Simonovich
  • Ganshina Tamara Sergeevna
  • Kurza Elena Vladimirovna
  • Kurdyumov Ilya Nikolaevich
  • Turilova Antonina Ivanovna
  • Zhmurenko Lyudmila Mikhajlovna
  • Maslennikov Denis Vadimovich
  • Kovalev Georgij Ivanovich
  • Vasileva Ekaterina Vasilevna
RU2747202C2
COUMARIN, THIOCOUMARIN AND QUINOLINONE DERIVATIVES, HAVING ANTICONVULSANT ACTIVITY 2017
  • Mokrov Grigorij Vladimirovich
  • Litvinova Svetlana Aleksandrovna
  • Nerobkova Lyubov Nikolaevna
  • Kovalev Ivan Georgievich
  • Gudasheva Tatyana Aleksandrovna
  • Voronina Tatyana Aleksandrovna
  • Durnev Andrej Dmitrievich
  • Seredenin Sergej Borisovich
RU2720510C2
PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING PAROXYSMAL CONDITIONS 2011
  • Avakjan Gagik Norajrovich
  • Avakjan Georgij Gagikovich
  • Balaban'Jan Vadim Jur'Evich
  • Voronina Tat'Jana Aleksandrovna
  • Nerobkova Ljubov' Nikolaevna
RU2469722C1
ANTICONVULSANT AND TRANQUILISING AGENT 2015
  • Bespalov Aleksandr Yakovlevich
  • Matveeva Lidiya Petrovna
  • Petrov Aleksandr Nikolaevich
  • Savateeva Tatyana Nikolaevna
  • Chigareva Svetlana Mikhajlovna
RU2593885C1
3-BENZYLAMINOMETHYLENEPYRROLIDINE-2,4-DIONE AND ANTICONVULSANT AGENT BASED ON SAID 1997
  • Granik V.G.
  • Sorokina I.K.
  • Alekseeva L.M.
  • Mashkovskij M.D.
  • Parshin V.A.
  • Asnina V.V.
  • Parimbetova R.B.
  • Muzychenko A.P.
RU2144918C1
N-ACYL DERIVATIVES OF 4-PHENYLPYRROLIDINE-2-ONES SHOWING CEREBROPROTECTIVE (NOOTROPIC) ACTION 1990
  • Val'Dman A.V.
  • Voronina T.A.
  • Rakhmankulova I.Kh.
  • Glozman O.M.
  • Garibova T.L.
  • Meshcherjakova L.M.
  • Zhmurenko L.A.
  • Seredinin S.B.
  • Rozantsev G.G.
  • Tsenker L.
  • Vunderlikh G.
  • Lomann D.
  • Rostok A.
  • Zigemund Kh.
SU1746665A1

RU 2 744 758 C2

Authors

Voronina Tatyana Aleksandrovna

Litvinova Svetlana Aleksandrovna

Kutepova Inga Sergeevna

Nerobkova Lyubov Nikolaevna

Zhmurenko Lyudmila Aleksandrovna

Mokrov Grigorij Vladimirovich

Gudasheva Tatyana Aleksandrovna

Durnev Andrej Dmitrievich

Dates

2021-03-15Published

2018-10-19Filed