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2 538 982

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(51)

IPC

C07D307/78(2006-01-01)

C07D405/06(2006-01-01)

A61K31/343(2006-01-01)

A61K35/00(2006-01-01)

(21) (22)

Application

2013151510/04, 2013-11-19

(24)

Start date

2013-11-19

(22)

Actual filing date

2013-11-19

(45)

Published

2015-01-10

(72)

Inventor

Fedorov Aleksej Jur'EvichSitnikov Nikolaj SergeevichVojtovich Julija Valer'EvnaShchegravina Ekaterina SergeevnaSvirshchevskaja Elena Viktorovna

(73)

Holder

Federal'Noe Gosudarstvennoe Bjudzhetnoe Obrazovatel'Noe Uchrezhdenie Vysshego Professional'Nogo Obrazovanija Gosudarstvennyj Universitet Im. N.I. Lobachevskogo"

DERIVANT OF ACETAMID N-(1S)-1',2',3'-TRIMETHOXY-6,7-DIHYDRO-1H-BENZO[5',6':5,4]CYCLOHEPTA-[3,2-F]BENZOFURAN-1-IL) AND ITS APPLICATION Russian patent published in 2015 - IPC C07D307/78 C07D405/06 A61K31/343 A61K35/00

Abstract RU 2538982 C1

FIELD: biotechnologies.

SUBSTANCE: invention relates to new heterogeneous ring compounds containing a pentatomic rings, condensed with other nuclei, only with one atom of oxygen as a heteroatom, namely to derivants of acetamid N-((1S)-1',2',3'-trimethoxy-6,7-dihydro-1H-benzo[5',6':5,4]cyclohepta-[3,2-f]benzofuran-1-il) with the general formula 1 , where R - substituent, R=Ph, pyridine-2-il, CH₂OH, CH(CH₃)OH, CH₂CH₂OH, CH₂OAc, (CH₂)₈CO₂Me or CH₂N(CH₂CH₃)₂, and also to their application as an active component of antitumoral medicinal preparation.

EFFECT: increase of activity with inhibition of proliferation of the tumour cells.

10 cl, 3 dwg, 8 ex

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RU 2 538 982 C1

Authors

Fedorov Aleksej Jur'Evich

Sitnikov Nikolaj Sergeevich

Vojtovich Julija Valer'Evna

Shchegravina Ekaterina Sergeevna

Svirshchevskaja Elena Viktorovna

Dates

2015-01-10—Published

2013-11-19—Filed