FIELD: chemistry.
SUBSTANCE: invention relates to derivatives of 1'',2'',3''-trimethoxybenzo[5'',6'':5',4']1H-(aR, 1S)-1-acetamido-6',7'-dihydrocyclohepta[2',3'-f]-2,3-dihydrofuran of formula:
,
where X, Y, Z are substituents, X=H, Me, Y=H, Me, CF3, Cl, Z=H, H; O and its use as an active component of anticancer drugs for the treatment of cancer.
EFFECT: increase in apoptosis-inducing activity and activity in inhibiting the proliferation of tumor cells.
10 cl, 1 dwg, 1 tbl
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