FIELD: medicine.
SUBSTANCE: simulating this pathology is accompanied by pharmacological preconditioning. That is ensured by using Nicorandil in a single dose of 0.86 mg/kg of body weight which is introduced intragastrically through a probe in the form of a starch solution into a laboratory animal. Ischemia of the retina is simulated 30 minutes later by delivering mechanical pressure of 110 mm Hg on an anterior eye chamber for 30 minutes.
EFFECT: method provides the pronounced correction of ischemic ocular injuries.
1 ex, 1 tbl
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Authors
Dates
2015-01-20—Published
2013-07-09—Filed