METHOD OF TREATING PATIENT WITH HYPERTROPHIC CARDIOMYOPATHY Russian patent published in 2015 - IPC A61K31/4178 G01N33/49 A61P9/10 

Abstract RU 2540475 C1

FIELD: medicine.

SUBSTANCE: method involves recovering DNA, detecting polymorphism of AGTR1 gene coding angiotensin II receptor type 1. That is followed by detecting polymorphism of ACE gene coding angiotensin converting enzyme; in case of having combinations of AC(AGTR1)/ID(ACE) or AA(AGTR1)/DD(ACE) genotypes detected, angiotensin II receptor blockers, in particular losartan 50mg twice a day are prescribed as a part of the complex therapy.

EFFECT: invention enables developing the treatment procedure involving the angiotensin II receptor blockers taking into account its genetic traits for increasing the therapeutic effectiveness of both nonobstructive, and obstructive forms of hypertrophic cardiomyopathy.

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RU 2 540 475 C1

Authors

Chakova Natal'Ja Nikolaevna

Komissarova Svetlana Mikhajlovna

Nijazova Svetlana Sergeevna

Krupnova Ehvelina Vjacheslavovna

Mikhalenko Elena Petrovna

Chebotareva Natal'Ja Vjacheslavovna

Dates

2015-02-10Published

2013-07-12Filed