FIELD: medicine.
SUBSTANCE: method involves recovering DNA, detecting polymorphism of AGTR1 gene coding angiotensin II receptor type 1. That is followed by detecting polymorphism of ACE gene coding angiotensin converting enzyme; in case of having combinations of AC(AGTR1)/ID(ACE) or AA(AGTR1)/DD(ACE) genotypes detected, angiotensin II receptor blockers, in particular losartan 50mg twice a day are prescribed as a part of the complex therapy.
EFFECT: invention enables developing the treatment procedure involving the angiotensin II receptor blockers taking into account its genetic traits for increasing the therapeutic effectiveness of both nonobstructive, and obstructive forms of hypertrophic cardiomyopathy.
3 tbl, 2 ex
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Authors
Dates
2015-02-10—Published
2013-07-12—Filed