FIELD: medicine.
SUBSTANCE: method is implemented by evaluating the relation of GSK-3β/β-actin, calculating a composite score on SIGH-SAD scale. If observing an increase of the relation of GSK-3β/β-actin in blood mononuclear cells of the patients with depressive disorders of more than 0.70, and the total score on SIGH-SAD scale of more than 30, a severe current depressive episode accompanying a recurrent type of depressive disorder is predicted.
EFFECT: by evaluating the biological value, the method enables assessing the depression severity, holding the targeted rehabilitation psychotherapeutic and pharmacological measures.
1 tbl, 2 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD FOR ASSESSING SEVERITY OF A CURRENT DEPRESSIVE EPISODE IN COMORBIDITY OF AFFECTIVE AND PERSONALITY DISORDERS | 2015 |
|
RU2599975C1 |
| METHOD FOR PREDICTION OF COMORBID ANXIOUS DISORDER IN PATIENTS WITH RECURRENT DEPRESSIVE DISORDER | 2017 |
|
RU2644636C1 |
| ANTIDEPRESSIVE THERAPY | 2008 |
|
RU2379035C1 |
| METHOD FOR PREDICTION OF CLINICAL EFFECTIVENESS IN DEPRESSIVE EPISODE | 2013 |
|
RU2530635C1 |
| METHOD FOR PREDICTION OF COMORBID COURSE OF AFFECTIVE DISORDERS AND ALCOHOLISM BASED ON DETERMINATION OF BLOOD SERUM PROTEINS | 2021 |
|
RU2767699C1 |
| METHOD FOR PREDICTING RECURRENT RISK IN CLINICAL COURSE OF DEPRESSIVE DISORDERS AFTER CARRYING OUT ANTIDEPRESSANT THERAPY | 2004 |
|
RU2266048C2 |
| METHOD FOR PREDICTING THERAPY EFFICIENCY FOR PATIENTS WITH ADJUSTMENT DISORDERS WITH ANXIETY-DEPRESSIVE SYMPTOMATIC | 2018 |
|
RU2677867C1 |
| METHOD FOR PREDICTING THE DEVELOPMENT OF A CHRONIC COURSE OF A DEPRESSIVE DISORDER | 2017 |
|
RU2657193C9 |
| METHOD FOR PREDICTING TREATMENT EFFECTIVENESS IN PATIENTS SUFFERING FROM DEPRESSIVE DISORDERS CAUSED BY SELECTIVE SEROTONINERGIC ANTIDEPRESSANTS | 2000 |
|
RU2177253C1 |
| THERAPY OF DEPRESSIONS | 2008 |
|
RU2364425C1 |
