FIELD: medicine.
SUBSTANCE: invention refers to experimental medicine and concerns simulating panctreatopathy caused by administering a non-steroidal anti-inflammatory drug (NSAID-panctreatopathy). The method involves the oral administration of Nise® into a laboratory rat in a single dose of 5 mg/kg of animal's body weight for 21 days.
EFFECT: method provides stimulating NSAID-panctreatopathy close to real clinical conditions, when using therapeutic doses of the preparation, leading to developing pathomorphological changes specific for a toxic drug-induced pancreatic injury.
3 ex
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Authors
Dates
2015-02-20—Published
2013-11-29—Filed