METHOD FOR SIMULATING NSAID- PANCREATOPATHY EXPERIMENTALLY Russian patent published in 2015 - IPC G09B23/28 

Abstract RU 2541739 C1

FIELD: medicine.

SUBSTANCE: invention refers to experimental medicine and concerns simulating panctreatopathy caused by administering a non-steroidal anti-inflammatory drug (NSAID-panctreatopathy). The method involves the oral administration of Nise® into a laboratory rat in a single dose of 5 mg/kg of animal's body weight for 21 days.

EFFECT: method provides stimulating NSAID-panctreatopathy close to real clinical conditions, when using therapeutic doses of the preparation, leading to developing pathomorphological changes specific for a toxic drug-induced pancreatic injury.

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RU 2 541 739 C1

Authors

Kosareva Polina Vladimirovna

Lazarenko Ljudmila Viktorovna

Samodelkin Evgenij Ivanovich

Khorinko Vitalij Petrovich

Chereshnev Valerij Aleksandrovich

Dates

2015-02-20Published

2013-11-29Filed