FIELD: medicine.
SUBSTANCE: present invention relates to a liposome formulation for use in a method of treating or preventing tuberculosis, as well as to a suspension containing a dissolved liposomal formulation. Liposome formulation comprises fragments from a Mycobacterium tuberculosis-complex strain, liposome forming agent, 2-6% (w/v) sucrose. Liposomal formulation is characterized by a z- average size of the particles which is 110 nm or less.
EFFECT: invention makes it possible to obtain a formulation with high bioavailability and efficacy.
23 cl, 13 dwg, 6 tbl, 12 ex
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Authors
Dates
2018-03-28—Published
2012-01-04—Filed