COMPOSITIONS, DIAGNOSTIC TECHNIQUES AND METHOD OF TREATING RENAL DISORDERS IN DOGS Russian patent published in 2015 - IPC G01N33/52 G01N33/53 A61P13/12 

Abstract RU 2546016 C2

FIELD: medicine.

SUBSTANCE: group of inventions refers to medicine and concerns a diagnostic technique for renal disorders in dogs involving the stage of measuring an expression of biomarker group in a dog's biological sample, wherein the biomarkers represent clusterin (CLU), secreted frizzle-bound protein-2 (SFRP2); matrilin-2 (Matn2); lumican (LUM); decorin (DCN); alpha 1 (III) of collagen chain, variant 12 (COL3A1); retinol-binding protein 4 (rbp4); MMP-9; transferrin (TF); Apo-C-1 (ApoC1); and inhibin-beta A (INHBA). Besides, the group of inventions refers to a method of treating, relieving or delaying the renal disorders; a nucleic acid probe that is fragmented cRNA and hybridised with dog's gene; using the probe for preparing a kit applicable in accordance with the above method.

EFFECT: group of inventions provides diagnosing the renal disorders in dogs.

18 cl, 6 ex, 5 tbl

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RU 2 546 016 C2

Authors

Al'-Murrani Samer

Malladi Sukkhasvami

Gao Sjanmin

Dates

2015-04-10Published

2010-12-23Filed