FIELD: medicine.
SUBSTANCE: group of inventions refers to medicine and concerns a diagnostic technique for renal disorders in dogs involving the stage of measuring an expression of biomarker group in a dog's biological sample, wherein the biomarkers represent clusterin (CLU), secreted frizzle-bound protein-2 (SFRP2); matrilin-2 (Matn2); lumican (LUM); decorin (DCN); alpha 1 (III) of collagen chain, variant 12 (COL3A1); retinol-binding protein 4 (rbp4); MMP-9; transferrin (TF); Apo-C-1 (ApoC1); and inhibin-beta A (INHBA). Besides, the group of inventions refers to a method of treating, relieving or delaying the renal disorders; a nucleic acid probe that is fragmented cRNA and hybridised with dog's gene; using the probe for preparing a kit applicable in accordance with the above method.
EFFECT: group of inventions provides diagnosing the renal disorders in dogs.
18 cl, 6 ex, 5 tbl
Title | Year | Author | Number |
---|---|---|---|
DIAGNOSTIC TECHNIQUE AND KIT FOR DIAGNOSING GLOMERULONEPHITIS IN CAT | 2011 |
|
RU2564122C2 |
COMPOSITIONS AND METHODS FOR DIAGNOSING AND MONITORING HYPERTHYROIDISM IN FELINES | 2012 |
|
RU2593952C2 |
MARKERS FOR ENDOMETRIAL CANCER | 2010 |
|
RU2596394C2 |
COMPOSITIONS AND METHODS FOR DIAGNOSING AND TREATING HYPERTHYROIDISM OF COMPANION ANIMALS | 2012 |
|
RU2612901C2 |
COMPOSITIONS AND METHODS FOR TREATMENT OF OSTEOARTHRITIS | 2009 |
|
RU2619553C2 |
TISSUE-SPECIFIC BIOMARKERS OF AGEING | 2010 |
|
RU2557313C2 |
METHOD FOR DETECTION OF MALIGNANT TUMOURS | 2009 |
|
RU2519089C2 |
GENE INVOLVED IN IMMORTALISATION OF HUMAN CANCER CELL AND USE THEREOF | 2007 |
|
RU2449016C2 |
METHOD FOR DETECTING MALIGNANT TUMOURS | 2014 |
|
RU2671497C2 |
IMMUNITY INDUCING AGENT | 2009 |
|
RU2511039C2 |
Authors
Dates
2015-04-10—Published
2010-12-23—Filed