COMPOSITIONS AND METHODS HAVING EFFECT ON SATURATION, LIPID METABOLISM AND FAT INTAKE Russian patent published in 2015 - IPC A61K31/20 

FIELD: medicine, pharmaceutics.

SUBSTANCE: group of inventions is based on using as a part of compositions, combinations and devices related to a phenotype involving a decrease of body fat and plasma triglycerides, and an increase of saturation of two or more chemically synthesised or chemically modified polynucleotides, which are specifically hybridised with two or more polynucleotide targets, which are differentially expressed in animals showing the phenotype involving the decrease of body fat and plasma triglycerides and the increase of saturation as a result of the continuous regular administration of a substance which has an effect on one or more parameters of nutrient absorption, saturation, lipid metabolism and fat recovery, wherein the polynucleotide targets contain a gene specified in genes coding FAS proteins, vistafin and GPR119.

EFFECT: group of inventions enables identifying the new compounds having the effect on one or more of these parameters and modulating the related animal's phenotype.

17 cl, 2 tbl, 2 ex