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2 484 132

(13)

(51)

IPC

C12N5/00(2006-01-01)

C12N15/63(2006-01-01)

C12N15/86(2006-01-01)

(21) (22)

Application

2010118428/10, 2008-10-08

(24)

Start date

2008-10-08

(22)

Actual filing date

2008-10-08

(45)

Published

2013-06-10

(72)

Inventor

Brauler Dzh. MarkKumar PrasannaStorkus Uolter Dzh.Okada Khidekho

(73)

Holder

Intrekson KorporejshnJuniversiti Of Pittsburg Of Ze Kommonvelt Sistem Of Khajer Ehd'Jukejshn

MODIFIED DENDRITE CELLS AND THEIR USE IN TREATMENT OF MALIGNANT TUMOURS Russian patent published in 2013 - IPC C12N5/00 C12N15/63 C12N15/86

Abstract RU 2484132 C2

FIELD: biotechnologies.

SUBSTANCE: vector is proposed for controlled expression of protein, having a function of interleukine-12, and also the method to produce modified in vitro dendrite cells and appropriate cells, which express interleukin-12 in a controlled manner, under control of the system of gen expression modulation in presence of activating ligand.

EFFECT: invention may be used in therapy for treatment of animals, including a human being.

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RU 2 484 132 C2

Authors

Brauler Dzh. Mark

Kumar Prasanna

Storkus Uolter Dzh.

Okada Khidekho

Dates

2013-06-10—Published

2008-10-08—Filed