FIELD: chemistry.
SUBSTANCE: group of inventions relates to biotechnology, in particular to peptydoglycane hydrolase biosynthesis, and represents a protein with the peptydoglycane hydrolase activity, a plasmid, containing a peptydoglycane hydrolase-coding fragment, a bacterium-producer, a method of microbiological peptydoglycane hydrolase synthesis, as well as a pharmaceutical composition, containing the obtained peptydoglycane hydrolase, for the therapy of diseases, caused by Gram-negative microflora.
EFFECT: elaborated method of microbiological synthesis makes it possible to obtain bacteriophage S-394 peptydoglycane hydrolase in an effective way.
22 cl, 2 dwg, 9 ex
| Title |
Year |
Author |
Number |
| STRAIN Escherichia coli - PRODUCER OF HYDROLASE OF ALPHA-AMINO ACIDS FROM Xanthomonas rubrilineans, AND METHOD FOR MICROBIOLOGICAL SYNTHESIS OF HYDROLASE OF ALPHA-AMINO ACIDS ESTERS BASED ON ABOVE SAID STRAIN |
2012 |
- Berezina Oksana Valentinovna
- Skljarenko Anna Vladimirovna
- Abesheva Zajan Andreevna
- Satarova Dzhenni Ehrnstovna
- Jarotskij Sergej Viktorovich
- Tishkov Vladimir Ivanovich
- Fedorchuk Vladimir Vital'Evich
- Fedorchuk Elena Aleksandrovna
- Savin Svjatoslav Sergeevich
|
RU2502797C1 |
| ESCHERICHIA COLI L-ASPARAGINASE PRODUCER AND EXPRESSION PLASMID pET28a-AsnSYN CODING L-ASPARAGINASE |
2023 |
- Gabidova Alfiya Erkinovna
- Nikitin Dmitrij Valerevich
- Romanova Yuliya Dzhafarovna
- Vorobev Ivan Ivanovich
- Orlova Nadezhda Aleksandrovna
- Shajfutdinov Rolan Rustemovich
|
RU2817891C1 |
| pETTvDAO2 RECOMBINANT PLASMID PROVIDING SYNTHESIS OF YEAST Trigonopsis variabilis D-AMINO ACID OXYDASE (DAO) IN Escherichia coli CELLS AND RECOMBINANT Escherichia coli STRAIN C41(DE3)/pETTvDAO2 AS PRODUCER OF DAO |
2006 |
- Ehl'Darov Mikhail Anatol'Evich
- Redo Vadim Aleksandrovich
- Zhgun Aleksandr Aleksandrovich
- Zejnalov Orkhan Akhmed Ogly
- Skrjabin Konstantin Georgievich
|
RU2310687C1 |
| ARTIFICIAL GENE, CODING CIMERIC PROTEIN OF HUMAN ANGIOGENIN, CHIMERIC PLASMID pJZZ-A, ENSURING EXPRESSION OF GENE OF CHIMERIC PROTEIN OF HUMAN ANGIOGENIN IN Escherichia coli AND STRAIN OF Escherichia coli BL21(DE3)/pJZZ-A-PRODUCENT OF RECOMBINANT CHIMERIC PROTEIN OF HUMAN ANGIOGENIN |
2012 |
- Ramazanov Jurij Akhmetovich
- Beklemishev Anatolij Borisovich
|
RU2512527C2 |
| RECOMBINANT PLASMID DNA pQE-70_LysAP46 PROVIDING SYNTHESIS OF RECOMBINANT PROTEIN LysAP46, STRAIN OF ESCHERICHIA COLI BACTERIA - PRODUCER OF RECOMBINANT PROTEIN LysAP46 AND RECOMBINANT PROTEIN LysAP46, WHICH HAS ANTIBACTERIAL EFFECT |
2022 |
- Tikunova Nina Viktorovna
- Morozova Vera Vitalevna
- Golosova Nataliya Nikolaevna
- Kozlova Yuliya Nikolaevna
- Khlusevich Yana Aleksandrovna
|
RU2809842C1 |
| RECOMBINANT PLASMID DNA pEstPc, ENCODING POLYPEPTIDE WITH PROPERTIES OF ESTERASE Psychrobacter cryohalolentis K5, Escherichia coli BACTERIA STRAIN - PRODUCER OF POLYPEPTIDE WITH PROPERTIES OF ESTERASE Psychrobacter cryohalolentis K5
|
2011 |
- Novototskaja-Vlasova Ksenija Aleksandrovna
- Petrovskaja Lada Evgen'Evna
- Shcherbakova Viktorija Arturovna
- Rivkina Elizaveta Mikhajlovna
- Gilichinskij David Abramovich
|
RU2478708C1 |
| RECOMBINANT PLASMID DNA pEst877 DETERMINING EXPRESSION OF POLYPEPTIDE WITH ACTIVITY OF ESTERASE Psychrobacter cryohalolentis K5 ON CELL SURFACE Escherichia coli, AND BACTERIA STRAIN Escherichia coli BL21 (DE3) pLysS/pEst877-PRODUCER OF POLYPEPTIDE WITH ACTIVITY OF ESTERASE PSYCHROBACTER CRYOHALOLENTIS K5 ON CELL SURFACE |
2013 |
- Petrovskaja Lada Evgen'Evna
- Krjukova Elena Aleksandrovna
- Novototskaja-Vlasova Ksenija Aleksandrovna
- Rivkina Elizaveta Mikhajlovna
- Dolgikh Dmitrij Aleksandrovich
- Kirpichnikov Mikhail Petrovich
|
RU2526213C1 |
| RECOMBINANT PLASMID PET21-TF7, PROVIDING SYNTHESIS OF MODIFIED TISSUE FACTOR, AND ESCHERICHIA COLI BL21 (DE3) PET21-TF7 STRAIN - PRODUCER OF RECOMBINANT HUMAN TISSUE FACTOR |
2020 |
- Shcherbakov Dmitrij Nikolaevich
- Elchaninov Vadim Valentinovich
- Shanshin Daniil Vasilevich
- Balabova Dina Vladimirovna
- Koval Anatolij Dmitrievich
- Erin Dmitrij Nikolaevich
|
RU2744592C1 |
| FUSED PROTEIN OF THIOREDOXIN AND INFESTIN 4 DOMAIN, METHOD FOR PREPARING IT, EXPRESSION PLASMID DNA CODING FUSED PROTEIN, AND BACTERIUM Escherichia coli TRANSFORMED BY THIS PLASMID DNA |
2012 |
- Vorob'Ev Ivan Ivanovich
- Orlova Nadezhda Aleksandrovna
- Koljadko Vladimir Nikolaevich
|
RU2528251C2 |
| RECOMBINANT PLASMID DNA PET3.54, ENCODING POLYPEPTIDE FN3.54, INTERACTING WITH HUMAN TUMOUR NECROSIS FACTOR, AND STRAIN OF BACTERIA ESCHERICHIA COLI - PRODUCER OF POLYPEPTIDE FN3.54, INTERACTING WITH HUMAN TUMOUR NECROSIS FACTOR |
2013 |
- Shingarova Ljudmila Nikolaevna
- Petrovskaja Lada Evgen'Evna
- Krjukova Elena Aleksandrovna
- Boldyreva Elena Filippovna
- Dolgikh Dmitrij Aleksandrovich
- Kirpichnikov Mikhail Petrovich
|
RU2531547C1 |
