AMINO AMIDES IN BACTERIOCHLOROPHYLL A SERIES, HAVING PHOTODYNAMIC ACTIVITY AND METHOD FOR PRODUCTION THEREOF Russian patent published in 2015 - IPC A61K31/409 A61K47/30 C07D487/22 

Abstract RU 2548675 C9

FIELD: chemistry.

SUBSTANCE: invention relates to amino amides in the bacteriochlorophyll a series, having the general formula: where n=2, 4, 8, 10, having photo-induced anti-tumour activity, and to a method for production thereof by reacting methyl ether of bacteriopheophorbide a with a diaminoalkane of formula NH2(CH2)nNH2, where n=2, 4, 8, 10, in pyridine.

EFFECT: obtaining highly efficient photosensitisers, amino amides in the bacteriochlorophyll a series based on bacteriochlorin e, having high photo-induced anti-tumour activity.

2 cl, 4 dwg, 11 ex

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RU 2 548 675 C9

Authors

Mironov Andrej Fedorovich

Reshetnikov Roman Igorevich

Grin Mikhail Aleksandrovich

Jakubovskaja Raisa Ivanovna

Plotnikova Ekaterina Aleksandrovna

Morozova Natal'Ja Borisovna

Tsygankov Anatolij Anatol'Evich

Feofanov Aleksej Valer'Evich

Ermakova Dar'Ja Ehduardovna

Efremenko Anastasija Vladimirovna

Dates

2015-04-20Published

2013-05-29Filed