PHOTOSENSITISER FOR TREATMENT OF CANCER DISEASES AND METHOD OF ITS OBTAINING Russian patent published in 2018 - IPC A61K31/40 A61K41/00 A61P35/00 A61P31/04 

FIELD: pharmacology.

SUBSTANCE: group of inventions relates to the field of pharmacology, namely to photosensitisers based on chlorin e6. Photosensitiser for the treatment of cancer diseases contains chlorin e6 salt with N-methyl-D-glucamine (meglumine) and L-lysine in molar ratios of 1:2:1 and has the structural formula (I):

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Also a method for the preparation of the photosensitiser for the treatment of cancer diseases is disclosed, which consists in adding to chlorin e6 salt the calculated amounts of N-methyl-D-glucamine (C₇H₁₇NO₅) and L-lysine (C₆H₁₄N₂O₂) to the chlorin e6 salt, necessary to form the formula of salt (I), followed by filtration of the received solution of chlorin e6 double salt.

EFFECT: group of inventions provides the increased photo-induced activity of the photosensitiser during the photodynamic therapy of cancer diseases.

5 cl, 1 dwg, 5 ex, 2 tbl