PHOTOSENSITISER BASED ON BACTERIOCHLORIN p DERIVATIVE, METHOD OF OBTAINING BACTERIOCHLORIN p DERIVATIVE AND METHOD OF PHOTODYNAMIC THERAPY OF CANCER WITH APPLICATION OF SAID PHOTOSENSITISER Russian patent published in 2011 - IPC A61K31/409 A61K9/10 A61N5/67 A61P35/00 C07D487/22 B82B1/00 

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention relates to photosensitiser, which represents nanostructured water dispersion based on bacteriochlorin p derivative, namely methyl ester of O-ethyloxime N-etoxycycloimide bacteriochlorin p C₃₈H₄₆N₆O₆. Invention also relates to method of said photosensitiser obtaining, including reaction of methyl ester of bacteriopurpurin in main solvent with etoxyamine chlorhydrate at room temperature for 72-80 hours, which is finished after displacement of spectral maximum of reaction mixture absorption to 802 nm. Invention also relates to method of photodynamic therapy, which includes introduction of said photosensitiser and irradiation of pathologic part with optic irradiation in spectrum range 790-810 nm 0.7-5 hours after introduction.

EFFECT: invention ensures high efficiency and selectivity of action of photodynamic therapy of large-size tumours and pigment tumours, including melanoma.

6 cl, 5 dwg, 6 ex