PHARMACEUTICAL COMPOSITION CONTAINING N-[3-CHLOR-4-[(3-FLUOROPHENYL)METHOXY]PHENYL]-6-[5[[[2-(METHYLSULPHONYL)ETHYL]AMINO]METHYL]-2-FURYL]-4-QUINAZOLINAMINE Russian patent published in 2015 - IPC A61K31/517 A61K47/00 A61K9/00 A61J3/10 A61P35/00 

Abstract RU 2548757 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: present invention refers to a pharmaceutical composition containing N-[3-chlor-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5[[[2-(methylsulphonyl)ethyl]amino]methyl]-2-furyl]-4-quinazolinamine or its pharmaceutically acceptable salt as an active pharmaceutical ingredient in an amount of more than 60 wt % to less than 85 wt % as related to total weight of the composition. The active pharmaceutical ingredient is characterised by a wetting angle of less than 55°.

EFFECT: method for preparing the pharmaceutical composition involves the stage of grinding or milling the above pharmaceutical ingredient in the presence of one or more excipients.

7 cl, 7 dwg, 5 tbl, 6 ex

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RU 2 548 757 C2

Authors

Katrin Rimkus

Frank Muskulus

Zandra Brjuk

Jana Pehtts

Dates

2015-04-20Published

2009-08-24Filed