METHOD FOR THERMAL CHEMORADIATION OF ADVANCED NON-SMALL CELL LUNG CANCER Russian patent published in 2015 - IPC A61K31/282 A61K31/337 A61P35/00 A61N5/00 

FIELD: medicine.

SUBSTANCE: there are involved local hyperthermia, teletherapy and chemotherapy. The chemotherapy is two-staged and follows the schedule: paclitaxel 175 mg/m² intravenously drop-by-drop for 3 hours and carboplatin AUC 6 intravenously drop-by-drop on the 1^st and 22^nd days. The teletherapy starts from the 3rd day in the multi-fractionation mode for 5 weeks in a dose of 1.3 Gy × 2 times a day to reach a total boost dose of 66 isoGy. The hyperthermia is conducted from the 1^st to 33^rd days of the chemotherapy 3 times a day, 15 sessions in all, 3 hours before administering the chemopreparations or conducting the radiation session to temperature 42 to 44°C for 60 min.

EFFECT: higher patient's survival rate ensured by reducing incidence of local recurrences and remotes metastases accompanied by improving acceptability of the treatment and quality of life.

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