METHODS AND PHARMACEUTICAL COMPOSITIONS FOR TREATING DOWN SYNDROME Russian patent published in 2015 - IPC A61K31/47 A61K31/551 A61P25/00 

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to a pharmaceutical composition applicable for treating Down syndrome mediated by Dyrkla activity. The composition contains a compound of formula I in an effective amount and a pharmaceutically acceptable carrier. In Formula I, each R₁ is independently specified in a group consisting of 3 and F; R₂ represents S; R₃ represents (CH₂)_m, wherein m is equal to 3; R₄ represents H; R₆ represents H; each R₈ is independently -OR₉ and each R₉ independently represents 3 or C_1-6alkyl.

EFFECT: invention refers to a method of treating Down syndrome mediated by Dyrkla activity.

7 cl, 1 dwg, 4 ex