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(19)

(11)

2 382 779

(13)

(51)

IPC

C07D401/12(2006-01-01)

C07D215/56(2006-01-01)

C07D209/12(2006-01-01)

C07D209/14(2006-01-01)

C07D209/18(2006-01-01)

C07D405/12(2006-01-01)

C07D409/12(2006-01-01)

C07D413/12(2006-01-01)

C07D417/12(2006-01-01)

A61K31/47(2006-01-01)

A61K31/4709(2006-01-01)

A61P25/00(2006-01-01)

A61P31/00(2006-01-01)

(21) (22)

Application

2007102578/04, 2005-06-24

(24)

Start date

2005-06-24

(22)

Actual filing date

2005-06-24

(45)

Published

2010-02-27

(72)

Inventor

Adida Rua Sara S.Khejzlvud Anna R.Grotenkhejs Peter D. J.Van Gur Frederik F.Singkh Ashvani K.Chzhou Tszinlan'Makkartni Dzhejson

(73)

Holder

Verteks Farmas'Jutikalz Inkorporejted

ATP-BINDING CASETTE TRANSPORTER MODULATORS Russian patent published in 2010 - IPC C07D401/12 C07D215/56 C07D209/12 C07D209/14 C07D209/18 C07D405/12 C07D409/12 C07D413/12 C07D417/12 A61K31/47 A61K31/4709 A61P25/00 A61P31/00

Abstract RU 2382779 C2

FIELD: chemistry.

SUBSTANCE: novel compound is N-(5-hydroxy-2,4-di-tert-butylphenyl)-4-oxo-1H-quinoline-3-carboxamide or its pharmaceutically acceptable salts. The invention also relates to a pharmaceutical composition.

EFFECT: obtaining a novel biologically active compound with CFTR activity modulation properties.

2 cl, 485 ex, 3 tbl

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RU 2 382 779 C2

Authors

Adida Rua Sara S.

Khejzlvud Anna R.

Grotenkhejs Peter D. J.

Van Gur Frederik F.

Singkh Ashvani K.

Chzhou Tszinlan'

Makkartni Dzhejson

Dates

2010-02-27—Published

2005-06-24—Filed