DIAGNOSTIC TECHNIQUE FOR TUBERCULOSIS INFECTION Russian patent published in 2013 - IPC G01N33/53 

FIELD: medicine.

SUBSTANCE: patient's peripheral blood is sampled; whole blood is incubated with and without mycobacterial antigens representing a mixture of the proteins ESAT-6, CFP-10, TB 7.7; the samples are centrifuged to recover plasma; the supernatant is examined for the IL-2 content, and the presence of the disease is diagnosed by a concentration difference in the samples as compared to the specified threshold value. The threshold value is the IL-2 concentration difference 36 pg/ml of the antigen-induced and spontaneous production, and if the concentration difference is 36 pg/ml and more, the tuberculosis infection is stated, while the values below the threshold show the absence of infection.

EFFECT: using the declared method enables the number of controversal results and improves the diagnostic reliability of the tuberculosis infection.

2 tbl, 3 dwg, 4 ex