DERIVATIVE OF HETEROCYCLIC CARBON ACIDS, WHICH CONTAIN 2,5,7-SUBSTITUTED OXAZOLOPYRIMIDINE RING Russian patent published in 2015 - IPC C07D498/04 A61K31/519 A61P17/02 A61P43/00 

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention relates to oxazolopyramidine compounds of formula (I), where A represents O; X represents (C₁-C₆)-alkanediyl or (C₁-C₆)-alkanediyloxy, where oxygen atom of (C₁-C₆)-alkanediyloxy is bound to group R²; Y represents pyrrolidinyl; R¹ represents (C₁-C₄)-alkyl; R² represents phenylene, optionally substituted by one or two carbon atoms in ring with similar or different substituent R²²; R³ is selected from group, which consists of cycloalkyl-C_uH_2u-, where u equals 1; radical of saturated 3-10-member monocyclic ring, phenyl or pyridyl, where ring radical is optionally substituted by one or two carbon atoms of ring with substituent R³¹; R⁴ represents hydrogen; R²² represents (C₁-C₄)-alkyl; R³¹ is selected from group, which consists of halogen and (C₁-C₄)-alkyl. Invention also relates to (S)-l-[2-(2,6-dimethyl-4-{5-[methyl-(3,3,3-trifluoropropyl)amino]-7-propoxyoxazolo[5,4-d]pyrimidine-2-yl}phenoxy)acetyl]pyrrolidine-2-carboxylic acid, pharmaceutical composition and to method of obtaining compounds of formula (I) .

EFFECT: compounds of formula (I), intended for activation of EDG-1 receptor and applied for wound healing.

16 cl, 2 tbl, 2 ex