METHOD FOR OBTAINING OF COMPOSITE SCAFFOLD FOR BONE TISSUE DEFECTS RESTORATION Russian patent published in 2017 - IPC A61L27/44 A61L27/12 A61L27/14 A61P19/00 

FIELD: medicine.

SUBSTANCE: method for composite scaffold obtaining for bone defects reconstruction is described, which includs synthesis of a polymer solution with a concentration of 9 wt % by polycaprolactone granular powder dilution in chloroform. Siliceous hydroxyapatite Ca₁₀(PO₄)_6-x(SiO₄)_x(OH)_2-x powder is added to the obtained polymer solution in the substitution x = 0.5 at a concentration of 5-15 wt % in the solution. The mixture is homogenized for at least 2 h, then a scaffold is formed by electric formation at a voltage of not less than 7 kV and a minimum distance of 50 mm between a die electrode in the form of a needle with an internal diameter of 0.55 mm and a deposition electrode in the form of a spinning shaft 60 mm in diameter.

EFFECT: method allows to improve the scaffolds surface wettability parameter.

3 dwg, 3 tbl