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2 556 609

(13)

(51)

IPC

G09B23/28(2006-01-01)

A61K31/195(2006-01-01)

A61P43/00(2006-01-01)

(21) (22)

Application

2014123957/14, 2014-06-10

(24)

Start date

2014-06-10

(22)

Actual filing date

2014-06-10

(45)

Published

2015-07-10

(72)

Inventor

Kolesnik Inga MikhajlovnaPokrovskij Mikhail VladimirovichLazarenko Viktor Anatol'Evich

(73)

Holder

Gosudarstvennoe Bjudzhetnoe Obrazovatel'Noe Uchrezhdenie Vysshego Professional'Nogo Obrazovanija Gosudarstvennyj Meditsinskij Universitet" Ministerstva Zdravookhranenija Rossijskoj Federatsii

METHOD FOR STIMULATING EXCISED LIVER REGENERATION WITH L-NORVALINE Russian patent published in 2015 - IPC G09B23/28 A61K31/195 A61P43/00

Abstract RU 2556609 C1

FIELD: medicine.

SUBSTANCE: stimulating the excised liver regeneration is ensured by a 70% hepatectomy into a laboratory animal on the second day of the experiment. A liver regeneration stimulator is presented by L-norvaline administered intragastrically in a daily dose of 10.0 mg/kg every 46 hours for the first 7 days of the experiment.

EFFECT: method provides the effective stimulation of the excised liver regeneration evidenced by reducing the animals' lethality, improved hepatic microcirculation, reduced manifestation of cytolysis and enhanced synthetic function of the liver.

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RU 2 556 609 C1

Authors

Kolesnik Inga Mikhajlovna

Pokrovskij Mikhail Vladimirovich

Lazarenko Viktor Anatol'Evich

Dates

2015-07-10—Published

2014-06-10—Filed