POLYCYCLIC COMPOUND AND METHODS OF THEIR APPLICATION Russian patent published in 2015 - IPC C07D495/04 C07D277/62 C07D333/54 C07D333/78 C07D495/20 A61K31/381 A61K31/428 A61P25/00 

Abstract RU 2557059 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention relates to compound of structural formula

,

which can be applied for treatment, prevention or carrying out treatment of neurological disorder. In formula (Iva) m is equal 0; n is equal 1; R1 and R2 are, each independently, hydrogen, C1-C4alkyl or C3-C6cycloalkyl; R3 and R4 are, each independently, hydrogen or C1-C4alkyl; R5 is hydrogen and R6 and R7 are, each independently hydrogen, halogen, C1-C4alkyl, C6-C10aryl, 5-10-membered heteroaryl, which contains one O atom, one S atom and/or 1-4 N atom(s), 3-8-membered heterocyclyl, containing 1-2 heteroatoms, selected from O, S and N, C1-C4alcoxyl or aminoC1-C4alkyl.

EFFECT: invention relates to pharmaceutical industry, which contains claimed compound, and to method of treatment, prevention or carrying out of treatment of neurological disorder such as psychosis or schizophrenia.

54 cl, 2 tbl

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RU 2 557 059 C2

Authors

Shao Limin

Kehmpbell Dzhon Ehmmerson

Kh'Juitt Majkl Charl'Z

Kehmpbell Una

Khananija Talin Dzh.

Dates

2015-07-20Published

2010-12-03Filed