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2 558 294

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IPC

C12N15/00(2006-01-01)

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Application

2014137218/10, 2014-09-16

(24)

Start date

2014-09-16

(22)

Actual filing date

2014-09-16

(45)

Published

2015-07-27

(72)

Inventor

Rizvanov Al'Bert Anatol'EvichBogov Andrej AlekseevichMasgutov Ruslan FaridovichBogov Aleksej AndreevichSalafutdinov Il'Nur Il'DusovichIsaev Artur AleksandrovichDeev Roman VadimovichBozo Il'Ja JadigerovichPlaksa Igor' Leonidovich

(73)

Holder

Obshchestvo S Ogranichennoj Otvetstvennost'Ju

CODON-OPTIMISED RECOMBINANT PLASMID, STIMULATION TECHNIQUE FOR PERIPHERAL NERVE REGENERATION, TREATMENT MODALITY FOR DAMAGED HUMAN NERVE Russian patent published in 2015 - IPC C12N15/00

Abstract RU 2558294 C1

FIELD: medicine.

SUBSTANCE: invention describes a gene therapeutic structure coding vascular endothelial growth factor (VEGF) and (FGF-2). Codon-optimised recombinant plasmid lies in the basis of gene therapeutic structure coding both factors. Introduction of gene therapeutic structure may be made directly to a damaged nerve and paraneural tissues both in intraoperative and postpoperative period. The invention may be used for stimulation of nerves regeneration.

EFFECT: invention improves significantly results of reparative treatment for damaged peripheral nerves.

3 cl, 15 dwg

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RU 2 558 294 C1

Authors

Rizvanov Al'Bert Anatol'Evich

Bogov Andrej Alekseevich

Masgutov Ruslan Faridovich

Bogov Aleksej Andreevich

Salafutdinov Il'Nur Il'Dusovich

Isaev Artur Aleksandrovich

Deev Roman Vadimovich

Bozo Il'Ja Jadigerovich

Plaksa Igor' Leonidovich

Dates

2015-07-27—Published

2014-09-16—Filed