FIELD: medicine.
SUBSTANCE: invention refers to medicine, namely gene therapy. What is proposed for consideration is a method for stimulating spinal regeneration by the introduction into an involved area of a vector on the basis of two-cartridge plasmid pBud-VEGF-FGF2 simultaneously expressing the combination of two cloned genes of neurotrophic and angiogenic human factors VEGF and FGF2.
EFFECT: use of the invention provides more effective spinal functional recovery that can find further application in treating the patients with traumatic spinal injuries.
3 cl, 3 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD FOR STIMULATING SPINAL CORD REGENERATION WITH GENETICALLY MODIFIED HUMAN UMBILICAL CORD BLOOD CELLS | 2013 |
|
RU2521225C2 |
| METHOD FOR STIMULATING NEUROTISATION USING NANOSTRUCTURED MATRIX AND GENETIC CONSTRUCTS | 2012 |
|
RU2517117C2 |
| AGENT FOR REPRESSION OF DEATH OF NEURONS IN ISCHEMIC STROKE OF BRAIN AND METHOD OF CELL-MEDIATED GENE THERAPY FOR ISCHEMIC STROKE OF BRAIN BY REPRESSION OF DEATH OF NEURONS IN ISCHEMIC STROKE OF BRAIN | 2017 |
|
RU2676701C1 |
| CODON-OPTIMISED RECOMBINANT PLASMID, STIMULATION TECHNIQUE FOR PERIPHERAL NERVE REGENERATION, TREATMENT MODALITY FOR DAMAGED HUMAN NERVE | 2014 |
|
RU2558294C1 |
| METHOD FOR TREATING TRAUMATIC SPINAL CORD INJURY | 2021 |
|
RU2758760C1 |
| METHOD FOR SIMULATING ANGIOGENESIS, TREATING NEUROGENERATIVE DISEASES AND REGENERATING SKELETAL MUSCLE USING PLASMID CONSTRUCTS WITH GENES FOR ANGIOGENIC AND NEUROTROPHIC FACTORS | 2020 |
|
RU2805082C2 |
| METHOD FOR PRODUCING PREPARATION OF GENETICALLY MODIFIED CELLS | 2009 |
|
RU2431669C2 |
| METHOD FOR PREPARING A CELL-MEDIATED GENE THERAPY AGENT AND A CELL-MEDIATED GENE THERAPY AGENT | 2019 |
|
RU2716013C2 |
| METHOD FOR STIMULATING SPINAL CORD REGENERATION BY MESENCHYMAL STEM CELLS, WHICH ARE INCLUDED IN THE FIBRIN MATRIX | 2016 |
|
RU2650638C1 |
| CODON-OPTIMISED SEQUENCES AND PHARMACEUTICAL COMPOSITION FOR RECOVERY OF BLOOD VESSELS | 2014 |
|
RU2557385C1 |
