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IPC

A61K31/7088(2006-01-01)

A61K48/00(2006-01-01)

A61P9/10(2006-01-01)

(21) (22)

Application

2017142047, 2017-12-01

(24)

Start date

2017-12-01

(22)

Actual filing date

2017-12-01

(45)

Published

2019-01-10

(72)

Inventor

Islamov Rustem RobertovichSokolov Mikhail EvgenevichBashirov Farid VagizovichMarkosyan Vage ArshalujsovichIzmajlov Andrej AleksandrovichFadeev Filip OlegovichKuznetsov Maksim SergeevichLisyukov Artur NikolaevichSafiullov Zufar ZufarovichKitaeva Endzhe AlbertovnaSalafutdinov Ilnur IldusovichShmarov Maksim MikhajlovichNaroditskij Boris Savelevich

(73)

Holder

Federalnoe Gosudarstvennoe Byudzhetnoe Obrazovatelnoe Uchrezhdenie Vysshego Obrazovaniya Gosudarstvennyj Meditsinskij Universitet" Ministerstva Zdravookhraneniya Rossijskoj FederatsiiIslamov Rustem RobertovichSokolov Mikhail Evgenevich

AGENT FOR REPRESSION OF DEATH OF NEURONS IN ISCHEMIC STROKE OF BRAIN AND METHOD OF CELL-MEDIATED GENE THERAPY FOR ISCHEMIC STROKE OF BRAIN BY REPRESSION OF DEATH OF NEURONS IN ISCHEMIC STROKE OF BRAIN Russian patent published in 2019 - IPC A61K31/7088 A61K48/00 A61P9/10

Abstract RU 2676701 C1

FIELD: medicine.

SUBSTANCE: invention relates to medicine and is intended for cell-mediated gene therapy for ischemic stroke. Therapeutic effective dose of genetic material consisting of a gene for vascular endothelial growth factor VEGF, a gene for glial neurotrophic factor GDNF and a gene for neuronal adhesion molecule NCAM, is directly administered by intrathecal injection within 4 hours after the onset of ischemic cerebral stroke.

EFFECT: invention provides a medicinal product for preventing and controlling the death of neurons in ischemic cerebral stroke.

1 cl, 2 dwg, 1 ex

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RU 2 676 701 C1

Authors

Islamov Rustem Robertovich

Sokolov Mikhail Evgenevich

Bashirov Farid Vagizovich

Markosyan Vage Arshalujsovich

Izmajlov Andrej Aleksandrovich

Fadeev Filip Olegovich

Kuznetsov Maksim Sergeevich

Lisyukov Artur Nikolaevich

Safiullov Zufar Zufarovich

Kitaeva Endzhe Albertovna

Salafutdinov Ilnur Ildusovich

Shmarov Maksim Mikhajlovich

Naroditskij Boris Savelevich

Dates

2019-01-10—Published

2017-12-01—Filed