FIELD: chemistry.
SUBSTANCE: group of inventions discloses antibody matrices for the determination of an activation condition and/or the total quantity of one or several oncogenic fused proteins in such biological samples as whole blood or a cancer tissue, as well as methods of application thereof. In some cases the activation condition and/or the total quantity of oncogenic fused protein in a sample can be measured in a combination with one or several molecules of signal transduction.
EFFECT: compositions and methods of the claimed invention possess advantages of specificity, associated with enzyme-linked immunosorbent assay, sensitivity, associated with signal amplification, and highly productive multiplexing, associated with micromatrices.
31 cl, 32 dwg, 10 ex, 3 tbl
