FIELD: chemistry.
SUBSTANCE: claimed is novel biologically active substance of class 5-aryl-2-heterylimino-3H-furan-3-one, namely to 5-phenyl-2-(3-cyano-4,5,6,7-tetrahydrobenzo[b]thien-2-yl)imino-2H-furan-3-one of formula 1. 5-phenyl-2-(3-cyano-4,5,6,7-tetrahydrobenzo[b]thiene-2-yl)imino-2H-furan-3-one 
is obtained by interaction of 5-phenylfurane-2,3-dione with 2-[(triphenylphosphoranyliden)amino]-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carbonitrile in medium of absolute toluene with mixing for 3 h at temperature 60°C, with the following extraction of target product by known methods.
EFFECT: compound with high output, possessing expressed antimicrobial and analgetic activity as well as low toxicity is obtained.
2 tbl, 4 ex
| Title |
Year |
Author |
Number |
| AMIDE (E)-2-AMINO-4-OXO-5-(2-OXO-2-PHENYLETHYLIDENE)-1-(3-ETHOXYCARBONYL)-4,5,6-7-TETRAHYDROBENZO[B]THIOPHEN-2-YL)4,5-DIHYDRO-1H-PYRROLE-3-CARBOXYLIC ACID, HAVING ANTIMICROBIAL ACTIVITY |
2020 |
- Shipilovskikh Sergej Aleksandrovich
- Rubtsov Aleksandr Evgenevich
- Makhmudov Ramiz Ragibovich
- Tkachenko Aleksandr Georgievich
- Nesterova Larisa Yurevna
|
RU2738405C1 |
| 4-BROMO-N'-((2-((2-(4-BROMOBENZOYL)-3-OXO-6-PHENYL-2,3-DIHYDROPYRIDAZIN-4-YL)AMINO)-4,5,6,7-TETRAHYDROBENZO[B]THIOPHEN-3-YL)(IMINO)METHYL)BENZOHYDRAZIDE, HAVING ANALGESIC ACTIVITY |
2024 |
- Shipilovskikh Sergei Aleksandrovich
- Makhmudov Ramiz Ragibovich
- Lipin Dmitrii Vladimirovich
|
RU2829963C1 |
| 1,6-DIOXO-1-METHOXY-6-PHENYL-2-CYANO-4-((3-CYANO-4,5,6,7-TETRAHYDROBENZO[B]THIOPHEN-2-YL)AMINO)HEXA-2,4-DIENE-3-OLATE OF POTASSIUM, HAVING ANTI-INFLAMMATORY ACTIVITY |
2024 |
- Shipilovskikh Sergej Aleksandrovich
- Makhmudov Ramiz Ragibovich
- Lipin Dmitrij Vladimirovich
|
RU2829961C1 |
| USE OF 5-(4-CHLOROPHENYL)-N-(3-CYANO-4,5,6,7-TETRAHYDROBENZO[b]THIOPHEN-2-YL)-1-ETHYL-1H-PYRAZOLE-3-CARBOXAMIDE AS AN ANTIMICROBIAL AGENT |
2023 |
- Uchuskin Maksim Grigorevich
- Mendogralo Elena Iurevna
- Makarov Anton Sergeevich
- Nikiforova Elena Aleksandrovna
- Rubtsov Aleksandr Evgenevich
- Panchenko Aleksei Olegovich
|
RU2809149C1 |
| 4-(4-METHOXYPHENYL)-4-OXO-N-PHENYL-2-((3-CYANO-4,5,6,7-TETRAHYDROBENZO[b]THIOPHEN-2-YL)AMINO)BUT-2-ENAMIDE WITH ANALGESIC ACTIVITY |
2023 |
- Shipilovskikh Sergei Aleksandrovich
- Makhmudov Ramiz Ragibovich
- Gorbunova Irina Aleksandrovna
|
RU2810072C1 |
| SODIUM 1-AMINO-1,6-DIOXO-6-(P-TOLYL)-2-CYANO-4-((3-CYANO-4,5,6,7-TETRAHYDROBENZO[b]THIOPHEN-2-YL)AMINO)HEXA-2,4-DIENE-3-OLATE, HAVING ANALGESIC ACTIVITY |
2024 |
- Shipilovskikh Sergei Aleksandrovich
- Makhmudov Ramiz Ragibovich
- Lipin Dmitrii Vladimirovich
|
RU2831124C1 |
| 4-OXO-N-(FURAN-2-YLMETHYL)-4-(4-CHLOROPHENYL)-2-((3-CYANO-4,5,6,7-TETRAHYDROBENZO[B]THIOPHEN-2-YL)AMINO)BUT-2-ENAMIDE WITH ANALGESIC ACTIVITY |
2022 |
- Shipilovskikh Sergei Aleksandrovich
- Makhmudov Ramiz Ragibovich
- Gorbunova Irina Aleksandrovna
- Okoneshnikova Elizaveta Aleksandrovna
|
RU2798425C1 |
| N'-(IMINO(2-((6-(2-METHOXYPHENYL)-2-(4-NITROBENZOYL)-3-OXO-2,3-DIHYDROPYRIDAZIN-4-YL)AMINO)-4,5,6,7-TETRAHYDROBENZO[B]THIOPHEN-3-YL)METHYL)-4-NITROBENZOHYDRAZIDE, HAVING ANTI-INFLAMMATORY ACTIVITY |
2024 |
- Shipilovskikh Sergej Aleksandrovich
- Makhmudov Ramiz Ragibovich
- Lipin Dmitrij Vladimirovich
|
RU2831250C1 |
| 2-CYANO-4-[1,6-DIOXO-6-(4-METHYLPHENYL)-1-ETOXY-4-(3-CYANO-4,5,6,7-TETRAHYDROBENZO[b]THIOPHEN-2-IL)AMINO]HEXA-2,4-DIEN-3-OLATE POTASSIUM WITH ANALGESIC ACTIVITY |
2022 |
- Shipilovskikh Sergei Aleksandrovich
- Makhmudov Ramiz Ragibovich
- Lipin Dmitrii Vladimirovich
- Kozlov Danil Anatolevich
|
RU2798429C1 |
| USE OF 4-(4-CHLOROPHENYL)-N-(3-CYANO-4,5,6,7-TETRAHYDROBEZO[b]THIOPHEN-2-YL)-3H-BENZO[b][1,4]DIAZEPINE-2-CARBOXAMIDE AS AN ANTIMICROBIAL AGENT |
2023 |
- Uchuskin Maksim Grigorevich
- Mendogralo Elena Iurevna
- Makarov Anton Sergeevich
- Nikiforova Elena Aleksandrovna
- Rubtsov Aleksandr Evgenevich
- Panchenko Aleksei Olegovich
|
RU2809055C1 |
