FIELD: chemistry.
SUBSTANCE: invention relates to amide (E)-2-amino-4-oxo-5-(2-oxo-2-phenylethylidene)-1-(3-(ethoxycarbonyl)-4,5,6,7-tetrahydrobenzo[b]thiophene-2-yl)-4,5-dihydro-1H-pyrrole-3-carboxylic acid of formula 1:
.
EFFECT: obtaining a compound with high output, having pronounced antimicrobial activity against gram-positive microorganisms, as well as low toxicity.
1 cl, 1 tbl, 3 ex
Title |
Year |
Author |
Number |
5-AMINO-1-(2-OXO-2-PHENYLETHYLIDENE)-3-(PYRROLIDINE-1-CARBONYL)-6,7,8,9-TETRAHYDROBENZO[4,5]THIENO[3,2-e]PYRROLO[1,2-a]PYRIMIDIN-2(1H)-ONE, WHICH HAS ANALGESIC ACTIVITY |
2023 |
- Parkhoma Kseniia Iurevna
- Lipin Dmitrii Vladimirovich
- Makhmudov Ramiz Ragibovich
- Shipilovskikh Sergei Aleksandrovich
|
RU2810252C1 |
(Z)-2-((4-R-5-R-3-(ETHOXYCARBONYL)THIOPHEN-2-YL)AMINO)-4-OXO-4-R-BUT-2-ENE ACIDS, HAVING ANTIMICROBIAL ACTIVITY |
2019 |
- Shipilovskikh Sergej Aleksandrovich
- Rubtsov Aleksandr Evgenevich
- Makhmudov Ramiz Ragibovich
|
RU2722176C1 |
ETHYL ETHER OF 2-(((Z)-AMINO((Z)-2,4-DIOXO-5-(2-OXO-2-PHENYLETHYLIDENE)PIRROLIDINE-3-YLIDEN)METHYL)AMINO)-4,5,6,7-TETRAHYDROBENZO[b]THIOPHENCARBOXYLIC ACID WITH ANALGETIC ACTIVITY |
2016 |
- Shipilovskikh Sergej Aleksandrovich
- Rubtsov Aleksandr Evgenevich
- Makhmudov Ramiz Ragibovich
- Vasileva Anastasiya Yurevna
|
RU2631649C1 |
APPLICATION OF ANTIMICROBIAL AGENT FOR GOLDEN STAPHYLOCOCCUS WITH MULTIPLE DRUG RESISTANCE BASED ON 2-((4-R1-5-R2-3-(ETHOXICARBONYL)THIOPHENE-2-YL)AMINO-4-R3-OXO-ENOIC ACIDS |
2021 |
- Shipilovskikh Sergej Aleksandrovich
- Rubtsov Aleksandr Evgenevich
- Makhmudov Ramiz Ragibovich
- Shipilovskikh Darya Aleksandrovna
- Tkachenko Aleksandr Georgievich
- Nesterova Larisa Yurevna
|
RU2763735C1 |
APPLICATION OF AN ANALGESIC AGENT BASED ON ETHYL ETHERS OF 2-[(5-HYDROXY-5-PHENYL-2-OXO-1-R-2,5-DIHYDRO-1H-PYRROLE-3-YL)AMINO]-4,5,6,7-TETRAHYDROBENZO[b]THIOPHENE-3-CARBOXYLIC ACID |
2021 |
- Shipilovskikh Sergej Aleksandrovich
- Rubtsov Aleksandr Evgenevich
- Makhmudov Ramiz Ragibovich
- Shipilovskikh Darya Aleksandrovna
|
RU2776072C1 |
ETHYL ETHER 2-AMINO-(3-CYANO-4,5,6,7-TETRAHYDROBENZO[B]THIOPHEN-2-YL)-5-(2-(4-ETHYLPHENYL)-2-OXOETHYLIDENE)-4-OXO- 4,5-DIHYDRO-1H-PYRROL-3-CARBOXYLIC ACID WITH ANALGESIC ACTIVITY |
2023 |
- Shipilovskikh Sergei Aleksandrovich
- Makhmudov Ramiz Ragibovich
- Lipin Dmitrii Vladimirovich
- Parkhoma Kseniia Iurevna
|
RU2810070C1 |
APPLICATION OF ANTIFUNGAL AGENT BASED ON 2-((4-R1-5-R2-3-(ETHOXYCARBONYL)THIOPHENE-2-IL)AMINO)-4-OXO-4-R3-BUT-2-ENO ACIDS IN RELATION TO CANDIDA ALDICANS |
2021 |
- Shipilovskikh Sergej Aleksandrovich
- Rubtsov Aleksandr Evgenevich
- Makhmudov Ramiz Ragibovich
- Shipilovskikh Darya Aleksandrovna
- Tkachenko Aleksandr Georgievich
- Nesterova Larisa Yurevna
|
RU2770598C1 |
BENZYLAMMONIUM SALT OF 4-ETHOXYCARBONYL-5-OXO-2-(2-OXO-2-PHENYLETHYLIDENE)-2,5-DIHYDRO-1H-PYRROLE-3-OLATE, SHOWING ANTIMICROBIAL ACTIVITY |
2022 |
- Ivanov Dmitrii Vladimirovich
- Igidov Nazim Musabekovich
- Balandina Svetlana Iurenva
|
RU2781135C1 |
APPLICATION OF 2-[(3-(AMINOCARBONIL)-4,5,6,7-TETRAHYDROBENZO[b]THIOPHEN-2-yl)AMINO]-4-OXO-4-(4-CHLOROPHENYL)BUT-2-ENOIC ACID IN AS AN ANTI-INFLAMMATORY DRUG |
2022 |
- Shipilovskikh Sergei Aleksandrovich
- Makhmudov Ramiz Ragibovich
- Rubtsov Aleksandr Evgenevich
|
RU2785780C1 |
USE OF AN ANTIFUNGAL AGENT BASED ON ETHYL ESTER OF 2-[(5-(4-METHOXYPHENYL)-2-OXOFURAN-3(2H)-YLIDENE)AMINO]-4,5,6,7-TETRAHYDROBENZO[b]THIOPHENE-3-CARBOXYLIC ACID |
2021 |
- Shipilovskikh Sergej Aleksandrovich
- Rubtsov Aleksandr Evgenevich
- Makhmudov Ramiz Ragibovich
- Shipilovskikh Darya Aleksandrovna
- Tkachenko Aleksandr Georgievich
- Nesterova Larisa Yurevna
|
RU2766564C1 |