METHOD OF DIFFERENTIAL DIAGNOSTICS OF CERVICAL INTRAEPITHELIAL NEOPLASIA OF III DEGREE AND PRE-INVASIVE CERVICAL CANCER, ASSOCIATED WITH HUMAN PAPILLOMA VIRUS Russian patent published in 2014 - IPC A61B5/00 G01N33/48 

FIELD: medicine.

SUBSTANCE: invention relates to field of medicine, namely to diagnostics of malignant neoplasms by immunologic methods. Laboratory analysis is carried out. In course of laboratory analysis the following immunologic parameters are determined: content of CD10×10⁹/l, CD20×10⁹Al, CD25×l0⁹/l lymphocytes of peripheral blood, functional reserve of cervical mucus neutrophils, level of blood IL-10, and levels of blood IFN-γ and TNF-α of cervical mucus. On the basis of obtained data calculated is parameter, the value of which is used to diagnose carcinoma in situ or cervical intraepithelial neoplasia of III degree.

EFFECT: method makes it possible to perform differential diagnostics of cervical carcinogenesis stages, and thus improve approaches to treatment of women with severe dysplasia and pre-invasive cervical cancer and preserve full reproductive function in said category of patients.

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