FIELD: chemistry.
SUBSTANCE: invention relates to a method of producing a compound of formula and a salt thereof, which includes reacting a compound of formula or a salt thereof with a hydrazine monohydrate, where R is C1-C6 alkyl; where the compound of formula (5) or a salt thereof is obtained by reacting a compound of formula or a salt thereof with 4-fluorobenzaldehyde in the presence of a reducing agent and an acid or a Lewis acid, where R is C1-C6 alkyl. The invention also relates to alternative methods of producing a compound of formula (1) and to intermediate compounds whose structural formulae are given in the claim.
EFFECT: obtaining a compound of formula (1) using novel methods with improved output and obtaining novel intermediate compounds.
47 cl, 14 ex
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Authors
Dates
2015-09-10—Published
2011-02-08—Filed