METHOD FOR PREDICTION OF CLINICAL COURSE OF POST-SPLENECTOMY IMMUNE THROMBOCYTOPENIA BY SPLENIC CD8+T-LYMPHOCYTE WEIGHT Russian patent published in 2015 - IPC G01N33/53 

FIELD: medicine.

SUBSTANCE: after splenectomy, spleen is weighed; a CD8+ T-lymphocyte count is measured morphometrically in histologic sections of a lymphoid organ after immune histochemical staining. A weight is calculated by formula: M = m × D/100%, wherein M is the CD8+ T-lymphocyte weight (g), m is the spleen weight (g), D is the CD8+ T-lymphocyte count, %. If the CD8+ T-lymphocyte value is ≥9.75 g, the refractory clinical course of immune thrombocytopenia is predicted, whereas the value of <9.75 g enables stating the form of post-splenectomy immune thrombocytopenia with the favourable clinical course.

EFFECT: using the given method enables predicting the clinical course of post-splenectomy immune thrombocytopenia and applying a differentiated approach to prescribing a therapy.

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