FIELD: medicine.
SUBSTANCE: invention discloses a method for producing a tabletted bivalent chemical cholera vaccine, which involves preparing and mixing lyophilised antigens - choleragen anatoxin, O-antigens - Inaba and Ogawa serovars with lactose monohydrate, microcrystalline cellulose, granulating a tablet mixture by fluid bed method with spraying 10% aqueous polyvinylpyrrolidone above, tabletting and covering 20% aqueous enteric coating.
EFFECT: higher yield of the chemical cholera vaccine tablets and the process of vaccine production safer for technological operators.
1 tbl, 2 ex
| Title | Year | Author | Number |
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| METHOD FOR PREPARING CHOLERAGEN ANATOXIN | 2013 |
|
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