FIELD: medicine.
SUBSTANCE: method involves recovering choleragen anatoxin by tangential ultrafiltration with the use of a membrane with the rated cut-off of a molecular weight of 300 kDa, concentrating by tangential ultrafiltration with the use of the membrane with the rated cut-off of a molecular weight of 30 kDa and purifying by diafiltration with a triple volume of sterile purified water by tangential ultrafiltration with the use of the membrane with the rated cut-off of a molecular weight of 30 kDa.
EFFECT: higher yield of choleragen anatoxin, reduced time and number of technological stages for preparing it.
1 dwg, 2 tbl, 1 ex
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