METHOD OF PREDICTING RISK OF DEVELOPMENT OF NEUROLOGICAL DEFICIENCY IN FULL-TERM NEW-BORN BABIES WITH HYPOXIC-ISCHEMIC BRAIN INJURY Russian patent published in 2015 - IPC A61B5/53 

FIELD: medicine.

SUBSTANCE: method of predicting risk of development of neurological deficiency in full-term new-born babies with hypoxic-ischemic brain injury includes clinical and neurosonographic detection of severe manifestations on 2-12 day of child's life. For this purpose MRT is carried out in mode of diffusion-weighted imaging, determined are: average value of measured diffusion coefficient (AVMDC) of white matter of brain at the level of anterior and posterior horns of lateral ventricles, bodies of lateral ventricles of both hemispheres and AVMDC of gray matter of cortex of frontal lobes and lenticular nuclei of both hemispheres. If AVMDC of brain white matter is from 1.62×10^-3 mm²/sec to 1.40×10^-3 mm²/sec, of gray substance of brain from 1.30×10^-3 mm²/sec 1.17×10^-3 mm²/sec, absence in future of stable neurological deficiency and development of functional disorders in child is predicted, which corresponds to cerebral ischemia of II degree. If AVMDC of white matter of brain is from 1.30×10^-3 mm²/sec to 0.69×10^-3 mm²/sec, of gray substance of brain is from 1.07×10^-3 mm²/sec to 0.64×10^-3 mm²/sec, development of stable neurological deficiency is predicted, which corresponds to cerebral ischemia of III degree.

EFFECT: method ensures high accuracy of determination of degree of brain tissue ischemia, which makes it possible to predict its outcome - further neurological development of child, absence or formation of neurological deficiency in them.

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