FIELD: chemistry.
SUBSTANCE: group of inventions relates to an immunogenic aqueous composition containing a biological antigen and an acrylic acid polymer, wherein said composition contains an electrolyte for providing osmotic concentration which is at least 30% higher than that of an aqueous solution of 0.9 wt/vol % sodium chloride. The group of inventions also relates to an injection composition and to use of an acrylic acid polymer in the aqueous composition.
EFFECT: group of inventions reduces pyrogenicity of immunogenic compositions while maintaining the titre of induced antibodies.
17 cl, 7 ex, 11 tbl
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