COMBINED VACCINE FOR INTRADERMAL ADMINISTRATION Russian patent published in 2025 - IPC A61K39/02 

FIELD: veterinary science.

SUBSTANCE: invention refers to veterinary vaccinology, namely to combined vaccines for pigs. Disclosed is a combined vaccine against porcine circovirus type 2 (PCV2) and Mycoplasma hyopneumoniae (Mhyo) pathogenic infection, containing non-replicating immunogen of porcine circovirus type 2 and non-replicating immunogen Mycoplasma hyopneumoniae, characterized by that the combined vaccine is an oil-in-water emulsion containing squalane, vitamin E-acetate and silicon dioxide. Also disclosed is the use of non-replicating immunogen of porcine circovirus type 2 and non-replicating immunogen Mycoplasma hyopneumoniae for the production of said combination vaccine for the preventive treatment of an animal against porcine circovirus type 2 infection and Mycoplasma hyopneumoniaeinfection, characterized by that the combined vaccine is introduced into the animal’s derma. What is disclosed is a method for preventive treatment of an animal against porcine circovirus type 2 infection and Mycoplasma hyopneumoniae infection by administering said combined vaccine into the animal’s derma. What is disclosed is an adjuvant composition for preparing a non-living vaccine, characterized by that the composition is an oil-in-water emulsion containing squalane, vitamin E-acetate and silicon dioxide.

EFFECT: invention provides a safe and effective vaccine against pathogenic infection with porcine circovirus type 2 (PCV2) and Mycoplasma hyopneumoniae (Mhyo) for transdermal administration.

14 cl, 12 tbl, 7 ex